HRID627132

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC1=CC(=O)CN(C(=O)OC(C)(C)C)[C@@H]1CO[Si](C)(C)C(C)(C)C

HCID89852188

未命名化合物

结构：CC(C)C1C=C(O[Si](C)(C)C)CN(C(=O)OC(C)(C)C)[C@@H]1CO[Si](C)(C)C(C)(C)C

HCID89852312

未命名化合物

2 次

PRODUCTS

生成物

结构：CC(C)C1=CC(=O)CN(C(=O)OC(C)(C)C)[C@@H]1CO[Si](C)(C)C(C)(C)C

HCID89851363

未命名化合物

收率 14.32%

PROCEDURE

实验过程

(S)-tert-butyl 2-((tert-butyldimethylsilyloxy)methyl)-3-isopropyl-5-oxo-5,6-dihydropyridine-1(2H)-carboxylate (804 mg, 14.32%) (over two steps) was prepared as described in Intermediate 78 as a yellow oil, using (6S)-tert-butyl 6-((tert-butyldimethylsilyloxy)methyl)-5-isopropyl-3-(trimethylsilyloxy)-5,6-dihydropyridine-1(2H)-carboxylate (Intermediate 88, theoretically 6.7 g, 14.64 mmol).