Thiophenol → HCID 131735283, compound

Participants

Reaction Steps

To a stirred suspension of Intermediate 120 (5 g, 9.47 mmol) and K2CO3 (7.86 g, 56.85 mmol) in acetonitrile (100 mL), PhSH (3.90 mL, 37.90 mmol) was added. The reaction was stirred at rt overnight. It was filtered and concentrated, then diluted with DCM and filtered through disposal filter. The filtrate was concentrated and purified by silica gel column (0-100% Hex/EA, 80 g ISCO) to afford the title compound (2.04 g, 63%) as an oil.

Provenance & Evidence