4-Bromoaniline → Ethyl 3-((4-bromophenyl)imino)-2-phenylpropanoate

HRID 627468Notes

Reaction equation

HRID 627468 reaction equation
O=[CH:2][CH:3]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:4]([O:6][CH2:7][CH3:8])=[O:5].[Br:15][C:16]1[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][CH:17]=1>CCO>[Br:15][C:16]1[CH:22]=[CH:21][C:19]([N:20]=[CH:2][CH:3]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:4]([O:6][CH2:7][CH3:8])=[O:5])=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 78074-BromoanilineHCID 562729Ethyl 3-oxo-2-phenylpropanoate

Product 1

HCID 86716060Ethyl 3-((4-bromophenyl)imino)-2-phenylpropanoate

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of ethyl 3-oxo-2-phenylpropanoate (3.50 g, 18.2 mmol) and 4-bromoaniline (2.60 g, 15.1 mmol) in EtOH (25 mL) was stirred at room temperature overnight and concentrated to give the title compound as an oil.

Workup

  1. concentrationconcentrated

Sources & evidence

ORD record
ord-950ad408894d4e028000a95f0be4dd70
Source dataset
uspto-grants-2016_04
Patent number
US09309222B2

Reaction notes

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