HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloronicotinoyl Chloride → 6-Chloro-N-methoxy-N-methylnicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloronicotinoyl Chloride | HCID 2782165 | — |
| Reactant | 2-Chloro-5-[(1-methyl-1H-imidazol-5-yl)carbonyl]pyridine | HCID 12016673 | — |
| Reactant | 2-Fluoropyridine-5-carbonyl chloride | HCID 14623602 | — |
| Reactant | 6-Fluoro-N-methoxy-N-methylpyridine-3-carboxamide | HCID 58767128 | — |
| Product | 6-Chloro-N-methoxy-N-methylnicotinamide | HCID 11435597 | — |
Reaction Steps
The title compound was prepared using 6-chloropyridine-3-carbonyl chloride (Intermediate 22, step a) in place of 6-fluoropyridine-3-carbonyl chloride according to the procedure described for Intermediate 21, step b.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09309222B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-523d37c3c2234f9c8e902158e9a2624a |
| Source note | uspto-grants-2016_04 |