化工社化工社 化学情報印刷レポート · 研究参考用
Methyl formate → CID 23682802
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl formate | HCID 7865 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 3,3-Dimethoxypropiononitrile | HCID 93731 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | CID 23682802 | HCID 23682802 | 46.2% |
反応手順
To a suspension of NaH (60% dispersion in mineral oil, 2.52 g, 63.0 mmol) in diethylether (75 mL) was added 3,3-dimethoxypropanenitrile (6.17 mL, 55.0 mmol) followed by methyl formate (6.74 mL, 110 mmol). The solution was stirred for 3 days at RT. The resulting solid was collected by vacuum filtration and washed with ether to afford sodium (E)-2-cyano-3,3-dimethoxyprop-1-en-1-olate (4.2 g, 25.4 mmol).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09309263B2 |
| 出典データセット | uspto-grants-2016_04 |
| ORD ID | ord-f2bbf5f441754157bfa1fa669e1873b6 |
| 出典メモ | uspto-grants-2016_04 |