HCID 68499992, compound → HCID 68499747, compound

HRID 627769Notes

Reaction equation

HRID 627769 reaction equation
[C:1]([O:5][C:6]([NH:8][C@@H:9]1[C:23](=[O:24])[N:22]2[CH2:25][C@H:26]([O:28][C:29]3[N:30]=[C:31]4[C:36](=[C:37]5[C:42]=3[CH:41]=[CH:40][C:39]([F:43])=[CH:38]5)[CH:35]=[C:34]([F:44])[CH:33]=[CH:32]4)[CH2:27][C@H:21]2[C:20](=[O:45])[NH:19][C@:18]2([C:47]([O:49]CC)=[O:48])[CH2:46][C@H:17]2[CH:16]=[CH:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C(OC(N[C@@H]1C(=O)N2C[C@H](OC3N=C4C(=C5C=3C=CC=C5)C=CC=C4)C[C@H]2C(=O)N[C@]2(C(OCC)=O)C[C@H]2C=CCCCCC1)=O)(C)(C)C>>[C:1]([O:5][C:6]([NH:8][C@@H:9]1[C:23](=[O:24])[N:22]2[CH2:25][C@H:26]([O:28][C:29]3[N:30]=[C:31]4[C:36](=[C:37]5[C:42]=3[CH:41]=[CH:40][C:39]([F:43])=[CH:38]5)[CH:35]=[C:34]([F:44])[CH:33]=[CH:32]4)[CH2:27][C@H:21]2[C:20](=[O:45])[NH:19][C@:18]2([C:47]([OH:49])=[O:48])[CH2:46][C@H:17]2[CH:16]=[CH:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 68499992HCID 68499992, compoundHCID 68500409HCID 68500409, compound

Product 1

HCID 68499747HCID 68499747, compound

Procedure

Example 38e was prepared according to the procedure used for the preparation of Example 24c, substituting the product of Example 38d for the product of Example 24b.

Workup

  1. customExample 38e was prepared
  2. customused for the preparation of Example 24c

Sources & evidence

ORD record
ord-26893d3545be4ea2977c8946cf386501
Source dataset
uspto-grants-2016_04
Patent number
US09309279B2

Reaction notes

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