HCID 178418546, compound → HCID 178509463, compound

HRID 627983Notes

Reaction equation

HRID 627983 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]2[C:11]3[S:12][C:13]([C:15]4[C:19]([C:20]5[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=5[Cl:26])=[CH:18][NH:17][N:16]=4)=[CH:14][C:10]=3[CH2:9][CH2:8][O:7][C:6]=2[CH:27]=1.[C:28]([Cu])#[N:29]>>[Cl:26][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[C:19]1[C:15]([C:13]2[S:12][C:11]3[C:5]4[CH:4]=[CH:3][C:2]([C:28]#[N:29])=[CH:27][C:6]=4[O:7][CH2:8][CH2:9][C:10]=3[CH:14]=2)=[N:16][NH:17][CH:18]=1

Participants

3

Reactant 2

HCID 178418546HCID 178418546, compoundHCID 178478016HCID 178478016, compound

Product 1

HCID 178509463HCID 178509463, compound

Procedure

Following the procedure of Example 53, 3-(8-bromo-4,5-dihydrobenzo[b]thieno[2,3-d]oxepin-2-yl)-4-(2-chlorophenyl)-1H-pyrazole and CuCN gave 275. MS: (ESI+) 404.1

Sources & evidence

ORD record
ord-e49200c467a74523934f67f9a77eaf46
Source dataset
uspto-grants-2016_04
Patent number
US09309265B2

Reaction notes

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