Hexanoic Acid → HCID 11855338, compound

HRID 628567Notes

Reaction equation

HRID 628567 reaction equation
[CH2:1]([CH:4]([CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH2:5][OH:6])[CH2:2][CH3:3].[C:12](O)(=[O:18])[CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]>O>[C:12]([O:6][CH2:5][CH:4]([CH2:1][CH2:2][CH3:3])[CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])(=[O:18])[CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]

Participants

4

Reactant 2

HCID 8892Hexanoic AcidHCID 248472-Propyl-1-heptanol

Product 1

HCID 11855338HCID 11855338, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

158.3 g 2-propylheptanol (1 mol) and 116.2 g caproic acid (1 mol) were heated for 4 h to 220° C. on a water separator together with 0.27 g Fascat® 2001 (Sn oxalate: 0.1% by weight, based on the composition as a whole). After the separation of water had stopped, the crude product was distilled in an oil pump vacuum through a 250 mm Vigreux column (T=111-126° C.). 251.4 g of a colorless oil were obtained: OHV=<1, AV=<0.1.

Workup

  1. customAfter the separation of water
  2. distillationthe crude product was distilled in an oil pump vacuum through a 250 mm Vigreux column (T=111-126° C.)

Sources & evidence

ORD record
ord-13e85112fdfa4bb4bee4080c220ef2b0
Source dataset
uspto-grants-2016_04
Patent number
US09314413B2

Reaction notes

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