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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 62860Generated: October 28, 2026

Bromomethylcyclopropane → 2-Cyclopropylmethylsulfanyl-nicotinic acid

https://huagongshe.com/reaction/62860

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromomethylcyclopropaneHCID 81503—
ReactantHCID 178524460HCID 178524460—
Product2-Cyclopropylmethylsulfanyl-nicotinic acidHCID 4356004988%

Reaction Steps

2-Mercapto-nicotinic acid (1 g, 6.4 mmol) and bromomethyl cyclopropane were reacted in the same manner as in Step A of Preparation Example 10 to obtain the title compound (1.19 g, 88%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447044B2
Source datasetuspto-grants-2016_09
ORD IDord-5ab7d3a4b66e4d23b1789e1f68485e78
Source noteuspto-grants-2016_09