反应详情

1,1,3,3-Tetrakis(trifluoromethylsulfonyl)propane [4] (148.8 mg, 0.264 mmol) was added to an acetonitrile (0.25 ml) solution of 4- t-butylphenol (43.6 mg, 0.29 mmol) at room temperature. After 1 hour of stirring, the reaction solution was concentrated under a reduced pressure. An obtained residue was purified by Kugelrohr distillation (190-210° C./5 mmHg) thereby obtaining 2-(2,2-bis(trifluoromethylsulfonyl)ethyl-4- t-butylphenol [1o] with an approximately quantitative yield (97.0 mg, 0.24 mmol).

1. concentrationthe reaction solution was concentrated under a reduced pressure
2. distillationAn obtained residue was purified by Kugelrohr distillation (190-210° C./5 mmHg)