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Part B. A solution of 4-(4-isopropyl-phenyl)-pyridine (1.01 g, 5.1 mmol) in dichloromethane (20 mL) is cooled to 0° C., and a solution of m-chloroperoxybenzoic acid (1.33 g, 7.6 mmol) in dichloromethane (20 mL) is added dropwise. The mixture is allowed to warm to ambient temperature over 12 h. with stirring, then heated to reflux for 2 h. An excess of m-chloroperoxybenzoic acid (0.5 g) is added, and reflux continued for 2 h. The solution is cooled and washed successively with 10% aq. sodium sulfite, 10% aq. sodium carbonate and saturated brine. The organic phase is dried over anhydrous magnesium sulfate and evaporated. The residue is separated by flash chromatography to afford 4-(4-isopropyl-phenyl)-pyridine-N-oxide (0.85 g, 78%).

1. temperatureheated
2. temperatureto reflux for 2 h
3. temperaturereflux
4. temperatureThe solution is cooled
5. washwashed successively with 10% aq. sodium sulfite, 10% aq. sodium carbonate and saturated brine
6. dry with materialThe organic phase is dried over anhydrous magnesium sulfate
7. customevaporated
8. customThe residue is separated by flash chromatography