Sodium Hydroxide → 3-(6-Phenyl-pyridin-2-yl)-benzoic acid

HRID 628846Notes

Reaction equation

HRID 628846 reaction equation
[C:1]1([C:7]2[N:12]=[C:11]([C:13]3[CH:14]=[C:15]([CH:20]=[CH:21][CH:22]=3)[C:16]([O:18]C)=[O:17])[CH:10]=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+]>>[C:1]1([C:7]2[N:12]=[C:11]([C:13]3[CH:14]=[C:15]([CH:20]=[CH:21][CH:22]=3)[C:16]([OH:18])=[O:17])[CH:10]=[CH:9][CH:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 69232498Methyl 3-(6-phenyl-pyridin-2-yl)-benzoate

Product 1

HCID 581569153-(6-Phenyl-pyridin-2-yl)-benzoic acid

Procedure

Part C. Methyl 3-(6-phenyl-pyridin-2-yl)-benzoate is saponified using sodium hydroxide, and workup afforded the acid title product. MS (ES+): m/e 276 (100).

Sources & evidence

ORD record
ord-8c97aff584b24374b8becd0194f90fc3
Source dataset
uspto-grants-2016_04
Patent number
US09315467B2

Reaction notes

Loading…