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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 628933Generated: October 30, 2026

Hexanoic acid, 2-hydroxy-, ethyl ester → Ethyl 2-{[tert-butyl(dimethyl)silyl]oxy}hexanoate

https://huagongshe.com/reaction/628933

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHexanoic acid, 2-hydroxy-, ethyl esterHCID 103589—
ReactantEthyl 3-((tert-butyldimethylsilyl)oxy)hexanoateHCID 14264095—
ProductEthyl 2-{[tert-butyl(dimethyl)silyl]oxy}hexanoateHCID 5743862074%

Reaction Steps

Ethyl 2-((tert-butyldimethylsilyl)oxy)hexanoate 5 (2.54 g) was prepared in 74% yield using ethyl 2-hydroxyhexanoate 4 according to the procedures described for compound 2 in above (See Schemes 1 and 2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315486B2
Source datasetuspto-grants-2016_04
ORD IDord-00d067e7cf0a4607a2a98b5a0ecc09f8
Source noteuspto-grants-2016_04