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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 628934Generated: October 31, 2026

Ethyl 2-{[tert-butyl(dimethyl)silyl]oxy}hexanoate → Dimethyl(3-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonate

https://huagongshe.com/reaction/628934

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-{[tert-butyl(dimethyl)silyl]oxy}hexanoateHCID 57438620—
ReactantDimethyl(4-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonateHCID 131735358—
ProductDimethyl(3-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonateHCID 13173535961%

Reaction Steps

Dimethyl (3-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonate 6 (1.56 g) was prepared in 61% yield using compound 5 according to the procedures described for compound 3 (see Schemes 1 and 2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315486B2
Source datasetuspto-grants-2016_04
ORD IDord-676cf8efc20d45da8d96a5029a53b91f
Source noteuspto-grants-2016_04