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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 628937Generated: October 31, 2026

Ethyl 6-hydroxyhexanoate → Ethyl 6-((tert-butyldimethylsilyl)oxy)hexanoate

https://huagongshe.com/reaction/628937

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 6-hydroxyhexanoateHCID 357781—
ReactantEthyl 3-((tert-butyldimethylsilyl)oxy)hexanoateHCID 14264095—
ProductEthyl 6-((tert-butyldimethylsilyl)oxy)hexanoateHCID 12547328990%

Reaction Steps

Ethyl 6-((tert-butyldimethylsilyl)oxy)hexanoate 8 (3.08 g) was prepared in 90% yield using ethyl 6-hydroxyhexanoate 7 according to the procedures described for compound 2 in above (see Schemes 1-3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315486B2
Source datasetuspto-grants-2016_04
ORD IDord-33b678d928f24c988ed33f52f0f4cbaa
Source noteuspto-grants-2016_04