HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 6-((tert-butyldimethylsilyl)oxy)hexanoate → Dimethyl(3-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 6-((tert-butyldimethylsilyl)oxy)hexanoate | HCID 125473289 | — |
| Reactant | Dimethyl(4-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonate | HCID 131735358 | — |
| Product | Dimethyl(3-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonate | HCID 131735359 | 60% |
Reaction Steps
Dimethyl(3-((tert-butyldimethylsilyl)oxy)-2-oxoheptyl)phosphonate 9 (1.55 g) was prepared in 60% yield using compound 8 according to the procedures described for compound 3 (see Schemes 1-3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09315486B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-16f0e30ac6db4cef83fe2aee21b5f561 |
| Source note | uspto-grants-2016_04 |