HCID 118036668, compound → HCID 91754676, compound

HRID 628939Notes

Reaction equation

HRID 628939 reaction equation
[Cl:1][C@H:2]1[C@H:6]([CH2:7][CH2:8][CH2:9][C:10]2[S:14][C:13]([C:15]([O:17]C)=[O:16])=[CH:12][CH:11]=2)[C@@H:5](/[CH:19]=[CH:20]/[C@@H:21]([OH:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][OH:27])[C@H:4]([OH:29])[CH2:3]1.Cl[C@H]1[C@H](CCCC2SC(C(O)=O)=CC=2)[C@@H](/C=C/[C@@H](O)CC(O)CCC)[C@H](O)C1>>[Cl:1][C@H:2]1[C@H:6]([CH2:7][CH2:8][CH2:9][C:10]2[S:14][C:13]([C:15]([OH:17])=[O:16])=[CH:12][CH:11]=2)[C@@H:5](/[CH:19]=[CH:20]/[C@@H:21]([OH:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][OH:27])[C@H:4]([OH:29])[CH2:3]1

Participants

3

Reactant 2

HCID 118036668HCID 118036668, compoundHCID 118037132HCID 118037132, compound

Product 1

HCID 91754676HCID 91754676, compoundYield 82%

Procedure

Compound 22 (31.8 mg) was prepared in 82% yield using compound 21 according to the procedures described for compound 14 (see Schemes 1-3).

Sources & evidence

ORD record
ord-2abb7d9f08e647a780e06ce94dc65c07
Source dataset
uspto-grants-2016_04
Patent number
US09315486B2

Reaction notes

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