Benzenesulfonyl chloride → HCID 70975362, compound

Participants

Reaction Steps

Phenyl sulfonyl chloride (0.02 ml, 1.3 eq.), Et3N (1 drop) was added to a stirred solution of 2-(4-amino-phenyl)-5-ethoxy-6-morpholin-4-yl-pyrimidine-4-carboxylic acid ethyl ester (40 mg, 1 eq.) in CH2Cl2 (2 ml) and the mixture was reacted overnight at r.t. The reaction mixture was extracted with EA and washed with brine. The crude was purified by chromatography to give a product (13 mg, 23.7%).

Provenance & Evidence