Hydrogen Peroxide → HCID 86673507, compound

Participants

Reaction Steps

The H2O2 (0.32 ml, 3.13 mmole) solution was added to a stirred solution of phenyl 4-(5-(methylthio)-4-morpholinopyrimidin-2-yl)phenylcarbamate (0.54 g, 1.28 mmole), CH2Cl2 (7 ml), Ac2O (0.13 ml), and silica gel (230-400 mesh, 200 mg). The solution was stirred at room temperature for 2-3 hrs, and quenched with NaHSO3(aq) (70 ml), and NaHCO3(aq) (70 ml), the solvent was removed, the residue was chromatographed to give the product (71%) as a white solid.

Provenance & Evidence