HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzaldehyde → 4-Isobutoxybenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | 1-Bromo-2-methylpropane | HCID 6555 | — |
| Product | 4-Isobutoxybenzaldehyde | HCID 249810 | 100.6% |
Reaction Steps
The compound was synthesized as in Example 24.1, using 4-hydroxybenzaldehyde (200 mg, 1.64 mmol) and isobutyl bromide (449 mg, 1.97 mmol) in place of 1-chloro-3,3-dimethylbutane (no sodium iodide was used) to give 4-isobutoxybenzaldehyde (294 mg, quant. crude) as a yellow oil that was used without further purification or characterization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09315495B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-e7477957f44c4f2ba7ccbb8b4cb40e2c |
| Source note | uspto-grants-2016_04 |