HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzaldehyde → 4-(Tetrahydrofuran-2-ylmethoxy)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Furan, 2-(bromomethyl)tetrahydro- | HCID 14501 | — |
| Product | 4-(Tetrahydrofuran-2-ylmethoxy)benzaldehyde | HCID 16227412 | 99.9% |
Reaction Steps
The compound was synthesized as in Example 24.1, using 4-hydroxybenzaldehyde (200 mg, 1.64 mmol) and 2-(bromomethyl)tetrahydrofuran (541 mg, 1.97 mmol) in place of 1-chloro-3,3-dimethylbutane (no sodium iodide was used) to give 4-((tetrahydrofuran-2-yl)methoxy)benzaldehyde (338 mg, quant. crude) as a yellow oil that was used without further purification or characterization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09315495B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-0784b84f5046440e93bb5b4c1db9d9ba |
| Source note | uspto-grants-2016_04 |