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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 62914Generated: October 26, 2026

4-Benzyl-1,3-oxazolidin-2-one → 2-(4-Benzyloxy-3-chloro-phenyl)-cyclopropane carboxylic acid

https://huagongshe.com/reaction/62914

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyl-1,3-oxazolidin-2-oneHCID 559668—
Reactant(R)-4-Benzyl-3-[2-(4-benzyloxy-3-chloro-phenyl)-cyclopropanecarbonyl]-oxazolidin-2-onHCID 90118050—
Product2-(4-Benzyloxy-3-chloro-phenyl)-cyclopropane carboxylic acidHCID 90118225—

Reaction Steps

(R)-4-Benzyl-3-[2-(4-benzyloxy-3-chloro-phenyl)-cyclopropanecarbonyl]-oxazolidin-2-on (132 mg, 0.28 mmol) was reacted in the same manner as in Step A of Preparation Example 59 to obtain the mixture (85 mg) of the title compound and 4-benzyloxazolidin-2-on.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447044B2
Source datasetuspto-grants-2016_09
ORD IDord-d06f0aa457ac41d9b25cb906f9fa82ad
Source noteuspto-grants-2016_09