HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromothiophene-2-carbaldehyde → 5-Ethyl-2-thiophenecarboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromothiophene-2-carbaldehyde | HCID 78428 | — |
| Reactant | Ethylboronic acid | HCID 521157 | — |
| Product | 5-Ethyl-2-thiophenecarboxaldehyde | HCID 169830 | 51% |
Reaction Steps
The compound was synthesized as in Example 3.1 using 5-bromothiophene-2-carbaldehyde (250 mg, 1.31 mmol) in place of 5-bromo-2-formylfuran and ethylboronic acid (160 mg, 2.16 mmol) in place of hexylboronic acid to give 5-ethylthiophene-2-carbaldehyde (93 mg, 51%). Used without further characterization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09315495B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-d38e02dffe8b4b98b8ba6e0d17297a59 |
| Source note | uspto-grants-2016_04 |