HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-1H-indole-2-carbaldehyde → 5-butyl-1H-indole-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-1H-indole-2-carbaldehyde | HCID 13522462 | — |
| Reactant | Potassium Butyltrifluoroborate | HCID 23693579 | — |
| Product | 5-butyl-1H-indole-2-carbaldehyde | HCID 118222784 | 28% |
Reaction Steps
5-Butyl-1H-indole-2-carbaldehyde was synthesized as in Example 3.1 using 5-bromo-1H-indole-2-carbaldehyde (300 mg, 1.34 mmol) in place of 5-bromo-2-formylfuran and potassium butyltrifluoroborate (352 mg, 2.21 mmol) in place of hexylboronic acid to give 5-butyl-1H-indole-2-carbaldehyde (75 mg, 28%). Used without further characterization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09315495B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-8969cf2de75e43a9ac7c4bbf7d30c1b7 |
| Source note | uspto-grants-2016_04 |