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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 629177Generated: November 2, 2026

HCID 118222818, compound → 1-Methyl-5-propoxy-1H-indole-2-carbaldehyde

https://huagongshe.com/reaction/629177

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 118222818HCID 118222818—
Reactant(1-methyl-5-propoxy-1H-indol-2-yl)methanolHCID 118222834—
Product1-Methyl-5-propoxy-1H-indole-2-carbaldehydeHCID 11822278675%

Reaction Steps

1-Methyl-5-propoxy-1H-indole-2-carbaldehyde (60 mg, 75% over two steps) was synthesized by the same reduction/oxidation sequence as in Example 52.1, using ethyl 1-methyl-5-propoxy-1H-indole-2-carboxylate (96 mg, 0.37 mmol) in place of methyl-6-butylbenzofuran-2-carboxylate, and (1-methyl-5-propoxy-1H-indol-2-yl)methanol (60 mg, 0.27 mmol) in place of (6-butylbenzofuran-2-yl)methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315495B2
Source datasetuspto-grants-2016_04
ORD IDord-f11569499b634fc6857f55b17ba147fe
Source noteuspto-grants-2016_04