1-Bromopropane → HCID 46941387, compound

HRID 629180Notes

Reaction equation

HRID 629180 reaction equation
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[C:4]([CH3:10])[CH:3]=1.Br[CH2:12][CH2:13][CH3:14]>>[CH3:10][C:4]1[CH:3]=[C:2]([O:1][CH2:12][CH2:13][CH3:14])[CH:9]=[CH:8][C:5]=1[CH:6]=[O:7]

Participants

3

Reactant 2

HCID 78401-BromopropaneHCID 4581854-Hydroxy-2-methylbenzaldehyde

Product 1

HCID 46941387HCID 46941387, compoundYield 71%

Procedure

The compound was synthesized as in Example 87.1, using 4-hydroxy-2-methylbenzaldehyde (54.4 mg, 0.40 mmol) in place of 4-hydroxybenzaldehyde and 1-bromopropane (98 mg, 0.80 mmol) in place of 1-iodo-(3,3,3-trifluoro)propane to give 2-methyl-4-propoxybenzaldehyde (50 mg, 71%). Used without further characterization.

Workup

  1. customThe compound was synthesized as in Example 87.1

Sources & evidence

ORD record
ord-4d4c0bbd06e24c7986d9cbc6f7ff3888
Source dataset
uspto-grants-2016_04
Patent number
US09315495B2

Reaction notes

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