化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl 3-(3,5-difluoro-4-hydroxyphenyl)propanoate → HCID 74222282、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 3-(3,5-difluoro-4-hydroxyphenyl)propanoate | HCID 23136305 | — |
| 反応物 | HCID 90118329 | HCID 90118329 | — |
| 生成物 | HCID 74222282 | HCID 74222282 | 60% |
反応手順
3-Chloromethyl-2-isobutylsulfanyl-pyridine (0.048 g, 0.22 mmol) obtained in Step C of Preparation Example 12 and 3-(3,5-difluoro-4-hydroxy-phenyl)-propionic acid ethyl ester (0.051 g, 0.22 mmol) obtained in Step D of Preparation Example 2 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (60% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09447044B2 |
| 出典データセット | uspto-grants-2016_09 |
| ORD ID | ord-1c20d20735884a058afc1bbdf2d9eb28 |
| 出典メモ | uspto-grants-2016_09 |