(4-Chloro-2-fluorophenyl)boronic acid → 6-Bromo-3-(4-chloro-2-fluorophenyl)imidazo[1,2-a]pyridine

Participants

Reaction Steps

The title compound, light brown solid (0.54 g, 76%), MS (ISP) m/z=327.3 [(M+H)+], mp 159° C., was prepared in accordance with the general method of intermediate E from commercially available 6-bromo-3-iodoimidazo[1,2-a]pyridine (0.7 g, 2.17 mmol) and commercially available 4-chloro-2-fluoro-phenylboronic acid (0.42 g, 2.38 mmol).

Provenance & Evidence