4-(Trifluoromethyl)phenylboronic acid → 6-Bromo-3-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine

Participants

Reaction Steps

The title compound, light brown solid (0.3 g, 40%), MS (ISP) m/z=341.4 [(M+H)+], mp 151° C., was prepared in accordance with the general method of intermediate E from commercially available 6-bromo-3-iodoimidazo[1,2-a]pyridine (0.7 g, 2.17 mmol) and commercially available 4-trifluoromethyl-phenylboronic acid (0.45 g, 2.38 mmol).

Provenance & Evidence