6-Bromo-3-(4-chlorophenyl)imidazo[1,2-a]pyridine → 3-(4-Chloro-phenyl)-6-[2-(4-chloro-phenyl)-2H-pyrazol-3-yl]-imidazo[1,2-a]pyridine

Participants

Reaction Steps

The title compound, off-white solid (41 mg, 31%), MS (ISP) m/z=405.3 [(M+H)+], mp 172.5° C., was prepared in accordance with the general method of example 1 from 6-bromo-3-(4-chloro-phenyl)-imidazo[1,2-a]pyridine (intermediate F) (0.1 g, 0.325 mmol) and 1-(4-chloro-phenyl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole (intermediate B) (0.12 g, 0.39 mmol).

Provenance & Evidence