6-Bromo-3-(4-fluorophenyl)-imidazo[1,2-a]pyridine → 3-(4-Fluoro-phenyl)-6-(2-p-tolyl-2H-pyrazol-3-yl)-imidazo[1,2-a]pyridine

Participants

Reaction Steps

The title compound, white solid (14 mg, 11%), MS (ISP) m/z=369.5 [(M+H)+], mp 141° C., was prepared in accordance with the general method of example 1 from 6-bromo-3-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine (intermediate E) (0.1 mg, 0.34 mmol) and 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-p-tolyl-1H-pyrazole (intermediate C) (0.083 g, 0.41 mmol).

Provenance & Evidence