HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromo-3-phenyl-imidazo[1,2-a]pyridine → 3-Phenyl-6-(2-p-tolyl-2H-pyrazol-3-yl)-imidazo[1,2-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromo-3-phenyl-imidazo[1,2-a]pyridine | HCID 52936844 | — |
| Reactant | 1-(4-methylphenyl)-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | HCID 90189234 | — |
| Product | 3-Phenyl-6-(2-p-tolyl-2H-pyrazol-3-yl)-imidazo[1,2-a]pyridine | HCID 76072526 | — |
Reaction Steps
The title compound, off-white solid (53 mg, 41%), MS (ISP) m/z=351.5 [(M+H)+], mp 107° C., was prepared in accordance with the general method of example 1 from 6-bromo-3-phenyl-imidazo[1,2-a]pyridine (intermediate G) (0.1 g, 0.366 mmol) and 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-p-tolyl-1H-pyrazole (intermediate C) (0.125 g, 0.44 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09315502B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-0bffb08aa61f4a6abcbe8cfd8d8ee268 |
| Source note | uspto-grants-2016_04 |