6-Bromo-3-(4-methoxyphenyl)imidazo[1,2-a]pyridine → 6-[2-(4-Fluoro-phenyl)-2H-pyrazol-3-yl]-3-(4-methoxy-phenyl)-imidazo [1,2-a]pyridine

Participants

Reaction Steps

The title compound, white solid (56 mg, 44%), MS (ISP) m/z=385.5 [(M+H)+], mp 162° C., was prepared in accordance with the general method of example 1 from 6-bromo-3-(4-methoxy-phenyl)-imidazo[1,2-a]pyridine (intermediate L) (0.1 g, 0.33 mmol) and 1-(4-fluoro-phenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (intermediate A) (0.11 mg, 0.38 mmol).

Provenance & Evidence