4-(6-Bromoimidazo[1,2-a]pyridin-3-yl)benzonitrile → 4-{6-[2-(4-Fluoro-phenyl)-2H-pyrazol-3-yl]-imidazo [1,2-a]pyridin-3-yl}-benzonitrile

Participants

Reaction Steps

The title compound, white solid (88 mg, 69%), MS (ISP) m/z=380.5 [(M+H)+], mp 215° C., was prepared in accordance with the general method of example 1 from 4-(6-bromo-imidazo[1,2-a]pyridin-3-yl)-benzonitrile (intermediate N) (0.1 g, 0.335 mmol) and 1-(4-fluoro-phenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (intermediate A) (0.13 mg, 0.44 mmol).

Provenance & Evidence