Methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate → [6-(6-Isopropylsulfanyl-pyridin-2-ylmethoxy)-2,3-dihydro-benzofuran-3-yl]-acetic acid

Participants

Reaction Steps

2-Chloromethyl-6-isopropylsulfanyl-pyridine (20 mg, 0.10 mmol) obtained in Step C of Preparation Example 16 and (6-hydroxy-2,3-dihydro-benzofuran-3-yl)-acetic acid methyl ester (20 mg, 0.10 mmol) obtained in Preparation Example 52 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (30 mg, 84%).

Provenance & Evidence