HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 629494Generated: October 30, 2026
Dimethylformamide dimethyl acetal → 3-(Dimethylamino)-1-(3-iodo-1-propan-2-ylpyrazol-4-yl)prop-2-en-1-one
https://huagongshe.com/reaction/629494
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | 1-(3-Iodo-1-isopropyl-1H-pyrazol-4-yl)ethanone | HCID 51034230 | — |
| Product | 3-(Dimethylamino)-1-(3-iodo-1-propan-2-ylpyrazol-4-yl)prop-2-en-1-one | HCID 70312565 | — |
Reaction Steps
A mixture of Intermediate 1-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)ethanone (5.0 g, 18.0 mmol) and N,N-dimethylformamide dimethyl acetal (50 mL) was heated at 155° C. for 20 h. The mixture was concentrated under vacuum to provide the crude title compound. MS m/z 334.0 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09314464B2 |
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| Source dataset | uspto-grants-2016_04 |
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| ORD ID | ord-5b1bb4a0e24b40f8971299d02905eb34 |
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| Source note | uspto-grants-2016_04 |
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