Ethyl 3-(3,5-difluoro-4-hydroxyphenyl)propanoate → 3-[3,5-Difluoro-4-(4-isopropylsulfanyl-2-methyl-pyrimidin-5-yl methoxy)-phenyl]-propionic acid ethyl ester

Participants

Reaction Steps

(4-Isopropylsulfanyl-2-methyl-pyrimidin-5-yl)-methanol (0.006 g, 0.03 mmol) obtained in Step B of Preparation Example 40 and 3-(3,5-difluoro-4-hydroxy-phenyl)-propionic acid ethyl ester (0.007 g, 0.03 mmol) obtained in Step D of Preparation Example 2 were reacted in the same manner as in Step A of Example 24 to obtain the title compound (0.009 g, 72%).

Provenance & Evidence