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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 629515Generated: October 26, 2026

Cyclopropylamine → 2-(4-(adamantan-1-yl)phenoxy)-N-cyclopropylacetamide

https://huagongshe.com/reaction/629515

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
ReactantPMID26882240-Compound-8HCID 625381—
Product2-(4-(adamantan-1-yl)phenoxy)-N-cyclopropylacetamideHCID 7154201188.2%

Reaction Steps

The title compound was prepared from 2-(4-(adamantan-1-yl)phenoxy)acetic acid (0.2 g, 0.69 mmol) and cyclopropylamine (0.039 g, 0.69 mmol) according to the example 1, which was given 2-(4-(adamantan-1-yl)phenoxy)-N-cyclopropylacetamide as a white solid (0.198 g, 87.4% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315507B2
Source datasetuspto-grants-2016_04
ORD IDord-f36380b57391480a98687b968e4bd324
Source noteuspto-grants-2016_04