Ethyl 3-(4-hydroxy-3-methoxyphenyl)propionate → 3-[4-(6-Cyclopentylsulfanyl-pyridin-2-ylmethoxy)-3-methoxy-phenyl]-propionic acid

Participants

Reaction Steps

2-Chloromethyl-6-cyclopentylsulfanyl-pyridine (33 mg, 0.14 mmol) obtained in Step C of Preparation Example 27 and 3-(4-hydroxy-3-methoxy-phenyl)-propionic acid ethyl ester (36 mg, 0.15 mmol) obtained in Step C of Preparation Example 38 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (32 mg, 69%).

Provenance & Evidence