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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 629542Generated: November 2, 2026

PMID26882240-Compound-8 → HCID 71542390, compound

https://huagongshe.com/reaction/629542

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPMID26882240-Compound-8HCID 625381—
Reactant(S)-1-Boc-3-methylpiperazineHCID 7023035—
ProductHCID 71542390HCID 7154239092.2%

Reaction Steps

The title compound was prepared from 2-(4-(adamantan-1-yl)phenoxy)acetic acid (0.2 g, 0.69 mmol) and (S)-tert-butyl 3-methylpiperazine-1-carboxylate (0.139 g, 0.69 mmol) according to the example 1, which was given (S)-tert-butyl 4-(2-(4-(adamantan-1-yl)phenoxy)acetyl)-3-methylpiperazine-1-carboxylate as a white solid (0.298 g, 91.2% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315507B2
Source datasetuspto-grants-2016_04
ORD IDord-943766ccc9c648c59c4e0e455db9ac85
Source noteuspto-grants-2016_04