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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 629543Generated: October 31, 2026

PMID26882240-Compound-8 → HCID 71542392, compound

https://huagongshe.com/reaction/629543

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPMID26882240-Compound-8HCID 625381—
Reactant(R)-1-Boc-3-methylpiperazineHCID 2756811—
ProductHCID 71542392HCID 7154239291.8%

Reaction Steps

The title compound was prepared from 2-(4-(adamantan-1-yl)phenoxy)acetic acid (0.2 g, 0.69 mmol) and (R)-tert-butyl 3-methylpiperazine-1-carboxylate (0.139 g, 0.69 mmol) according to the example 1, which was given (R)-tert-butyl 4-(2-(4-(adamantan-1-yl)phenoxy)acetyl)-3-methylpiperazine-1-carboxylate as a white solid (0.297 g, 91.0% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09315507B2
Source datasetuspto-grants-2016_04
ORD IDord-6bd7a8fa10f2440b94ce636365b4b958
Source noteuspto-grants-2016_04