HuagongsheHuagongshe Chemistry Print Report · For research reference only
PMID26882240-Compound-8 → HCID 86729437, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | PMID26882240-Compound-8 | HCID 625381 | — |
| Reactant | 1-(2-Propynyl)piperazine | HCID 14627369 | — |
| Product | HCID 71542395 | HCID 71542395 | — |
| Product | HCID 86729437 | HCID 86729437 | 178.9% |
Reaction Steps
The title compound was prepared from 2-(4-(adamantan-1-yl)phenoxy)acetic acid (0.13 g, 0.45 mmol) and 1-(prop-2-yn-1-yl)piperazine (0.056 g, 0.45 mmol) according to the example 1, which was given 2-(4-(adamantan-2-yl)phenoxy)-1-(4-(prop-2-yn-1-yl)piperazin-1-yl)ethanone as a white solid (0.158 g, 89.3% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09315507B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-2644df8b0997445092e14f0d26399b5c |
| Source note | uspto-grants-2016_04 |