PMID26882240-Compound-8 → 2-(4-(adamantan-1-yl)phenoxy)-N-(4-(1,1-dioxidothiomorpholino)phenyl)acetamide

Participants

Role	Name	HCID	Charge
Reactant	PMID26882240-Compound-8	HCID 625381	—
Reactant	4-(4-Aminophenyl)thiomorpholine 1,1-Dioxide	HCID 26370384	—
Product	2-(4-(adamantan-1-yl)phenoxy)-N-(4-(1,1-dioxidothiomorpholino)phenyl)acetamide	HCID 71542488	90.8%

Reaction Steps

The title compound was prepared from 2-(4-(adamantan-1-yl)phenoxy)acetic acid (0.2 g, 0.69 mmol) and 4-(4-aminophenyl)thiomorpholine 1,1-dioxide (0.158 g, 0.69 mmol) according to the example 1, which was given 2-(4-(adamantan-1-yl)phenoxy)-N-(4-(1,1-dioxidothiomorpholino)phenyl)acetamide as a white solid (0.31 g, 89.8% yield).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09315507B2
Source dataset	uspto-grants-2016_04
ORD ID	ord-dfb4ad196750429baa97b6d6c5d32662
Source note	uspto-grants-2016_04