HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate → HCID 74222794, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate | HCID 67812739 | — |
| Reactant | 3-Chloromethyl-2-cyclopentylsulfanyl-pyridine | HCID 90118283 | — |
| Product | HCID 74222794 | HCID 74222794 | 89% |
Reaction Steps
3-Chloromethyl-2-cyclopentylsulfanyl-pyridine (11 mg, 0.05 mmol) obtained in Step C of Preparation Example 8 and ((R)-6-hydroxy-2,3-dihydro-benzofuran-3-yl)-acetic acid methyl ester (10 mg, 0.05 mmol) obtained in Preparation Example 55 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (15 mg, 89%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447044B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-caeef8c9f1e846f8b2f07bcf69510a04 |
| Source note | uspto-grants-2016_09 |