HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → dimethyl-N-(4-(tert.-butoxycarbonylamino)-2-nitrobenzamido)-L-glutamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | N-(4-amino-2-nitrobenzamido)-L-glutamic acid-dimethylester | HCID 68702803 | — |
| Product | dimethyl-N-(4-(tert.-butoxycarbonylamino)-2-nitrobenzamido)-L-glutamate | HCID 68698082 | — |
Reaction Steps
The synthesis was achieved in analogy to example 3. From 17 g of dimethyl-N-(4-(tert.-butoxycarbonylamino)-2-nitrobenzamido)-L-glutamate 19.5 g of N-(4-amino-2-nitrobenzamido)-L-glutamic acid-dimethylester×trifluoroacetic acid salt were obtained which were used directly in example 4(c).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09315506B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-5bde1924c568462aa149d33395437843 |
| Source note | uspto-grants-2016_04 |