HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 629680Generated: October 30, 2026
n-(6-Nitro-2,3-dihydrobenzofuran-5-yl)acetamide → 6-Nitro-2,3-dihydrobenzofuran-5-amine
https://huagongshe.com/reaction/629680
Participants
| Role | Name | HCID | Charge |
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| Reactant | n-(6-Nitro-2,3-dihydrobenzofuran-5-yl)acetamide | HCID 13069186 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 6-Nitro-2,3-dihydrobenzofuran-5-amine | HCID 13069187 | 70.5% |
Reaction Steps
The product obtained in Step 4 (7.0 g, 31.5 mmol) and 2 mol/L H2SO4 solution (200 mL) were heated to reflux for 6 h. Then the reaction mixture was cooled to 0° C., filtered, washed with water, concentrated under vacuum and dried to obtain a product (4.0 g, 70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09315513B2 |
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| Source dataset | uspto-grants-2016_04 |
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| ORD ID | ord-71212763c13743369d9447afc60f9f06 |
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| Source note | uspto-grants-2016_04 |
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