HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloromethyl-6-isopropylsulfanyl-pyridine → HCID 90117995, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloromethyl-6-isopropylsulfanyl-pyridine | HCID 90118141 | — |
| Reactant | 2-(3-Chloro-4-hydroxy-phenyl)-cyclopropane carboxylic acid ethyl ester | HCID 90118199 | — |
| Product | HCID 90117995 | HCID 90117995 | 65% |
Reaction Steps
2-Chloromethyl-6-isopropylsulfanyl-pyridine (40 mg, 0.19 mmol) obtained in Step C of Preparation Example 16 and 2-(3-chloro-4-hydroxy-phenyl)-cyclopropane carboxylic acid ethyl ester (52 mg, 0.21 mmol) obtained in Step B of Preparation Example 47 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (42 mg, 65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447044B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-09d999504d114025a4cbb43e749367a9 |
| Source note | uspto-grants-2016_09 |