HCID 86726370, compound → HCID 86578126, compound

HRID 629769Notes

Reaction equation

HRID 629769 reaction equation
[N:1]([C@@H:4]([C@H:8]([C:17]1[CH:22]=[CH:21][C:20]([C:23]#[N:24])=[CH:19][CH:18]=1)[C:9]1[CH:14]=[CH:13][C:12]([F:15])=[C:11]([F:16])[CH:10]=1)[C:5](O)=[O:6])=[N+]=[N-].[NH2:25][C:26]1[CH:56]=[CH:55][CH:54]=[C:53]([F:57])[C:27]=1[CH2:28][CH2:29][C@H:30]1[O:35][CH2:34][C@@H:33]([CH2:36][O:37][C:38](=[O:45])[NH:39][CH2:40][C:41]([F:44])([F:43])[F:42])[N:32](C(OC(C)(C)C)=O)[CH2:31]1>>[C:23]([C:20]1[CH:21]=[CH:22][C:17]([C@H:8]([C:9]2[CH:14]=[CH:13][C:12]([F:15])=[C:11]([F:16])[CH:10]=2)[C@@H:4]([C:5]([NH:25][C:26]2[CH:56]=[CH:55][CH:54]=[C:53]([F:57])[C:27]=2[CH2:28][CH2:29][C@H:30]2[O:35][CH2:34][C@@H:33]([CH2:36][O:37][C:38](=[O:45])[NH:39][CH2:40][C:41]([F:44])([F:43])[F:42])[NH:32][CH2:31]2)=[O:6])[NH2:1])=[CH:18][CH:19]=1)#[N:24]

Participants

3

Reactant 2

HCID 86726370HCID 86726370, compoundHCID 86726378HCID 86726378, compound

Product 1

HCID 86578126HCID 86578126, compound

Procedure

The title compound was prepared from the product of step 1 and the product of step 4 of Example 99 using the procedures given in steps 2-4 of Example 93. MS (ES) m/z=664 (M+H)+.

Sources & evidence

ORD record
ord-f15aff2014a24e90822eb0b377edfb1e
Source dataset
uspto-grants-2016_04
Patent number
US09315475B2

Reaction notes

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