HCID 86726370, compound → HCID 86726388, compound

HRID 629779Notes

Reaction equation

HRID 629779 reaction equation
[N:1]([C@@H:4]([C@H:8]([C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=1)[C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)[C:5]([OH:7])=O)=[N+]=[N-].[NH2:22][C:23]1[CH:53]=[CH:52][CH:51]=[C:50]([F:54])[C:24]=1[CH2:25][CH2:26][C@H:27]1[O:32][CH2:31][C@@H:30]([CH2:33][O:34][C:35](=[O:42])[NH:36][CH2:37][C:38]([F:41])([F:40])[F:39])[N:29](C(OC(C)(C)C)=O)[CH2:28]1>>[F:21][C:18]1[CH:19]=[CH:20][C:15]([C@H:8]([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)[C@@H:4]([C:5]([NH:22][C:23]2[CH:53]=[CH:52][CH:51]=[C:50]([F:54])[C:24]=2[CH2:25][CH2:26][C@H:27]2[O:32][CH2:31][C@@H:30]([CH2:33][O:34][C:35](=[O:42])[NH:36][CH2:37][C:38]([F:39])([F:41])[F:40])[NH:29][CH2:28]2)=[O:7])[NH:1][C:35]([O:34][CH3:33])=[O:42])=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 86726370HCID 86726370, compoundHCID 86726389HCID 86726389, compound

Product 1

HCID 86726388HCID 86726388, compound

Procedure

The title compound was prepared from the product of step 1 and the product of step 4 of Example 99 using the procedures given in steps 2 and 3 of Example 93 and steps 1 and 2 of Example 91. MS (ES) m/z=680 (M+H)+.

Sources & evidence

ORD record
ord-df0716fc3e4740f88d22e5b3b98b8a04
Source dataset
uspto-grants-2016_04
Patent number
US09315475B2

Reaction notes

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