2-Chloromethyl-6-cyclobutylsulfanyl-pyridine → 2-[3-Chloro-4-(6-cyclobutylsulfanyl-pyridin-2-ylmethoxy)-phenyl]-cyclopropane carboxylic acid

Participants

Reaction Steps

2-Chloromethyl-6-cyclobutylsulfanyl-pyridine (52 mg, 0.26 mmol) obtained in Step C of Preparation Example 37 and 2-(3-chloro-4-hydroxy-phenyl)-cyclopropane carboxylic acid ethyl ester (70 mg, 0.29 mmol) obtained in Step B of Preparation Example 47 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (77 mg, 84%).

Provenance & Evidence